Several studies confirm the impact of erectile dysfunction on quality of life. Victims suffer from a real problem of identity with psychological and relational consequences. But do we need studies to confirm the evidence?
Questioning the masculine identity
Contrary to popular belief, these problems are more common than we think. After age 40, erectile dysfunction affects between 32 and 52% of men. But age is not the only risk factor. Thus the existence of associated chronic pathologies can blacken the picture: diabetes, high blood pressure, heart disease, depression, and prostatic diseases.
For men who suffer from erectile dysfunction and who want to end erectile dysfunction, several medical treatments have been proven to be available. To adopt the right treatment, it may be useful to take the time to look for the particularities, advantages and disadvantages of each of them.
During the past 20 years, treatments for impotence have particularly developed. Erectile dysfunction is no longer a taboo subject and men now have effective medical solutions to fight their erectile dysfunction. Read our guide on erectile dysfunction: www.smartcanadianpharmacy.com/erectile-dysfunction.html.
Because the offer has diversified considerably, the number of solutions available for impotence continues to grow. For this reason, it can be difficult to make the right choice when you first buy a drug for erectile dysfunction.
Although pharmaceutical companies have developed various forms of drugs for impotence, tablets remain the preferred choice for a large number of patients.
Levitra and Viagra tablets are two of the most effective solutions for men who want to fight their erectile dysfunction. It is legitimate to wonder about the differences between these drugs: do they have the same effectiveness? How long do the effects last?
Viagra and Levitra: effectiveness of each drug
Viagra was introduced to the market in 1998 by the manufacturer Pfizer is also considered the first sexual stimulant. Because of its color, it is also called “blue pill”. Not only is it the most famous drug but also it is the most sold in the world.
Levitra has also been on the market since 2003 and is produced by the manufacturer Bayer. It is particularly famous for its tolerability.
Comparison and dosage of active ingredients
- Viagra and Spedra have the highest concentrations of active substance. Brand Viagra contains 25mg, 50mg or 100mg of sildenafil active ingredient.
- Levitra has a wide range of doses of instant drugs, but with a lower concentration. The active ingredient Vardenafil is available in doses of 5 mg, 10 mg and 20 mg, while the orodispersible tablet is only available in 10 mg.
Duration of action
Despite the variety of active substances, sexual stimulants all act in the same way; they control the blood flow in the penis through the inhibitors of the enzyme PDE5. Nevertheless, the different sexual stimulants and dosages have their own duration of action. Viagra, Levitra and orodispersible Levitra work for five hours.
The most proven: Viagra
Brand Viagra is the first treatment for male impotence. With its success, it is also the most experienced. It is prescribed to millions of people each year and has revolutionized the treatment of erectile disorders in men.
Pharmaco-therapeutic class: urological; drugs used in erectile dysfunction, ATC Code: G04B E03.
Action mechanism
Sildenafil is an oral treatment for erectile dysfunction. Under natural conditions, that is, with sexual stimulation, it restores deficient erectile function by increasing blood flow to the penis.
The physiological mechanism responsible for erection of the penis involves the release of nitric oxide (NO) into the cavernous body during sexual stimulation. Nitrogen oxide then activates the enzyme guanylate cyclase, resulting in increased concentrations of cyclic guanosine monophosphate (cGMP) inducing relaxation of the smooth muscles of the cavernous body and promoting blood flow.
Sildenafil is a potent and selective inhibitor of cGMP-specific phosphodiesterase type 5 (PDE5) in cavernous bodies; this is where PDE5 is responsible for the degradation of cGMP. Sildenafil has a peripheral action site on erections. Sildenafil has no direct relaxant effect on isolated human cavernous body tissue, but it significantly accentuates the relaxing effects of NO on this tissue. When the NO / cGMP pathway is activated, such as during sexual stimulation, the inhibition of PDE5 by sildenafil results in an increase in cGMP concentrations in the cavernous body. Therefore, sexual stimulation is necessary for sildenafil to produce its beneficial pharmacological effects.
After taking the tablet about 30 minutes before the sexual act, the duration of action of Viagra is approximately 4 to 5 hours. The drug is effective in 80% of men, allowing them to recover a complete erection and adequate duration.
Contraindications and possible side effects of Viagra
Headaches and nausea may occur after taking Viagra. These side effects will however disappear quickly. If this is not the case, it is recommended to talk to a doctor.
People with cardiovascular disease or with blood pressure problems should not take Viagra. This contraindication can, however, be qualified and clarified by means of a medical consultation to ensure the patient’s safety regarding his medical condition.
Popularity and notoriety
Viagra is probably the best-known sexual stimulant on the market. Having been the first drug approved for the treatment of erectile dysfunction, it is known to most users.
Cialis is certainly the most popular: more than a third of patients opt for this drug, certainly for its duration of action superior to all competitors. Finally, Levitra and its very high tolerability convince about 20% of patients.
The most discreet and best tolerated: Levitra
Brand Levitra has been developed more recently to allow men with weaker health to benefit from erectile dysfunction treatment when other molecules have been contraindicated or have caused side effects. There is also a version in orodispersible tablets melting in the mouth for an easy and discreet grip.
Levitra has been available since March 31, 2003. It is the third drug in the class of phosphodiesterase 5 (PDE5) inhibitors, after Viagra and Cialis.
Advantages of Levitra
Tested on 3750 patients in its request for the European market, the Levitra was effective in many clinical situations: diabetes, hypertension, cardiovascular disease, hyperlipidemia, radical prostatectomy or depression.
Of a population of 430 diabetic men with erectile dysfunction for more than 6 months, the Levitra improved erections in 57% of patients treated with 10 mg and 72% of patients with 20 mg 2.
Efficacy has also been demonstrated on a population of 440 men who underwent radical prostatectomy with nerve sparing and having a usually severe erectile dysfunction. Erections were improved in 59% of patients who took with 10 mg and 65% of patients with 20 mg 3.
In other studies, the 20 mg dose provided sufficient erection for penetration as early as 15 minutes after administration in some men. The overall response of these subjects became significant compared to placebo 25 minutes after taking 4.
Other facts about Levitra
In addition to the competitive price, Levitra shares with its competitors other characteristics: same mode of administration, same mode of action, same contraindications (no association with nitrates). The conduct of comparative studies have shown more about the advantages and disadvantages of each drug in terms of side effects, effectiveness and tolerance. “Even before the results of these studies, one can as a doctor welcome an expanded offer of treatment in the face of a problem that has long been taboo,” concluded Dr. Sylvain Mimoun. It is enough now to dare to speak about it. If the first step is the most difficult, it is also the one that will return to a more fulfilling sexuality.
Levitra is effective in 30 to 60 minutes depending on the individual and its effect extends up to 6 hours after taking the tablet. Levitra orodispersible tablets allow a slightly faster action time (20 to 30 minutes) due to their shape favoring rapid absorption by the body.
Contraindications and possible side effects of Levitra
Levitra is a very well tolerated medicine for most men. It can be given in people with diabetes or with various health problems. The safety of Levitra should be validated for each case during a medical consultation.
Conclusion
You want to try for yourself? Order an online test pack. Since each man responds differently to the treatments, it may be that one treatment does not give enough effects or causes undesirable effects while another one will be better tolerated or more effective.
To allow you to test and find the product best suited to your condition; we offer you an impotence test pack including 2 products:
- Brand Viagra 25mg – 4 tablets
- Levitra Bayer 5mg – 4 tablets
When starting a treatment, it is recommended to start with the lowest dosage to test the tolerance of the organism to the product. If the treatment is not very effective, it is possible, with the doctor’s agreement, to increase the dosage later.
Important: Never take more than one medicine at a time during its 36-hour period of action so as not to put your health at risk.